Expression of the chemokine IP-10 (CXCL10) by hepatocytesin chronic hepatitis C virus infection correlates with histological severity and lobular inflammation

Abstract: The factors influencing lymphocyte trafficking to the liver lobule during chronic hepatitis C virus (HCV) infection are currently not well defined. Interferon-y-inducible protein 10 (IP-10), a chemokine that recruits activated T lymphocytes, has recently been shown by in situ hybridization to be expressed in the liver during chronic HCV infection

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