List of Articles

BOOKS

1.    Drug Metabolism and Alcohol.
R.C. Pirola.
ADIS Press, Sydney, 1977.

BOOK CHAPTERS

1.    Acute and Chronic Pancreatitis.
R.C. Pirola and C.S. Lieber.
Ch. 11 in Vol. III of the Biology of Alcoholism,
Ed.B. Kissin and H. Begleiter, Plenum Press, New York, 1974.

2.    Alcoholic Pancreatitis:  Experimental and Clinical Features.
C.S. Lieber, M.A. Korsten, and R.C. Pirola.
Ch.10, pp 412-435, “Medical Disorders of Alcoholism:
Pathogenesis and Treatment” Ed. C.S. Lieber,
W.B. Saunders and Co, Philadelphia, 1982.

3.    Gastrointestinal and Hepatic Diseases.
D.W. Piper, D.J. de Carle, W.F. Doe, M.C. Ngu,
G.O. Barbezat, R.C. Pirola, L.W. Powell, T.C. Sorrell
and R.K. Roberts.
Ch. XIX, pp 732-811, “Avery’s Drug Treatment: Principles
and Practice of Clinical Pharmacology and Therapeutics”,
Ed. T.M. Speight, 3rd Ed. ADIS Press, Auckland, 1987.

4.    Ethanol and the Pancreas.
Mark A. Korsten, Romano C. Pirola and Charles S. Lieber.
Ch. 11, pp 341-358, “Medical and Nutritional
Complications of Alcoholism: Mechanisms and Management”,
Ed. C.S. Lieber, Plenum Medical Book Company, New York,
1992.

5.    Acute pancreatitis.
Jeremy S. Wilson, Romano C. Pirola and Mark A.Korsten.
Ch.VII pp 474-492, “Medicine for the Practicing Physician” 4th Ed. Appleton & Lange,1996.

Apte MV, Pirola RC, Wilson JS. Etiopathogenesis and epidemiology of alcohol-induced acute pancreatitis in “The Pancreas : An integrated textbook of basic science, medicine and surgery”. Blackwell Publishing, Eds Beger H-G, Buchler M, Kozarek R, Lerch M, Neoptolemos J, Warshaw A, Whitcomb D and Shiratori K, Australia, ch.13, 2008.

Apte MV, Pirola RC, Wilson JS. Desmoplasia in pancreatic cancer : friend or foe? In “Surgery of Pancreatic Tumors” Eds Shrikhande S, Friess H, Buchler M., (accepted June 2006) in press.

Apte MV, Pirola RC, Wilson JS. Acetaldehyde and pancreatic MAP Kinases in “Acetaldehyde related pathology: bridging the trans-disciplinary divide.” Novartis Foundation, Eds Chadwick DJ and Goode J, Wiley, UK, pp200-211, 2007.

Apte MV, Pirola RC, Wilson JS. Desmoplasia in pancreatic cancer : friend or foe ? In ‘Surgery of Pancreatic Tumors’ Shrikhande S, Friess H, Buchler M ed(s), Bl Publications, New Delhi, pp.30-40, 2008

ARTICLES in PEER-REVIEWED JOURNALS

1.    Variable expression of hereditary elliptocytosis in one
family.
R.C. Pirola. Med. J. Aust. 1962, 2:1015-1017.

2.    Nutritional vitamin B12 deficiency.
P.M. Connor and R.C. Pirola.
Med. J. Aust. 1963, 2:451-453.

3.    The effects of ethyl alcohol on pancreatic exocrine
function.
A.E. Davis and R.C. Pirola.
Med. J. Aust. 1966, 2:757-760.

4.    Rapid duodenal intubation with metoclopramide.
R.C. Pirola.
Amer. J. Dig. Dis. 1967, 12:913-915.

5.    Whipple’s disease.
R.C. Pirola, M.A. Mishkel, G.J. Macdonald and A.G. Liddelow.
Med. J. Aust. 1967, 2:985-988.

6.    Absorption of phenoxymethyl penicillin in patients with steatorrhoea.
A.E. Davis and R.C. Pirola.
Aust. Ann. Med. 1968, 17:63-65.

7.    Exchange transfusion and liver perfusion in acute hepatitis coma.
R.C. Pirola, J.M. Ham and R.G. Elmslie
Med. J. Aust. 1968, 1:891-894.

8.    The effects of ethyl alcohol on sphincteric resistance at the choledochoduodenal junction in man.
R.C. Pirola and A.E. Davis.
Gut. 1968, 9:557-560.

9.    Pig liver perfusion for the treatment of acute hepatic coma.
J.M. Ham, R.C. Pirola, T.D. Bolin and R.G. Elmslie.
Amer. J.Dig. Dis. 1969, 14:239-244.

11.    Function of the isolated perfused pig liver.
J.M. Ham, R.C. Pirola and R.G. Elmslie.
Surg. Gynec. & Obstet. 1969, 14:470-474.

12.    Management of hepatic coma complicating acute viral hepatitis.
R.C. Pirola, J.M. Ham and R.G. Elmslie.
Gut. 1969, 10:898-903.

13.    Adaptation of intestinal lactase in the rat.
T.D. Bolin, R.C. Pirola and A.E. Davis.
Gastroenterology 1969, 57:406-409.

14.    Effects of pressure on the integrity of the duct-acinar system of the pancreas.
R.C. Pirola and A.E. Davis.
Gut 1970, 11:69-73.

15.    Effects of ethyl alcohol, d,l-ethionine and protein deficiency on rat pancreas.
R.C. Pirola, K.B. Taylor, A.E. Davis and A.G. Liddelow.
Amer. J. Dig. Dis. 1970, 15:21-30.

16.    Effects of intravenous alcohol on motility of the duodenum and of the Sphincter of Oddi.
R.C. Pirola and A.E. Davis.
Aust. Ann. Med. 1970, 19:24-29.

17.    Macromolecular assemblies of lipid in bile.
J.I. Howell, J.A. Lucy, R.C. Pirola and I.A.D. Bouchier.
Biochim. Biophys. Acta. 1970, 210:1-6.

18.    The Sphincter of Oddi and pancreatitis.
R.C. Pirola and A.E. Davis.
Amer. J. Dig. Dis. 1970, 15:583-588.

19.    Function of the liver after isolated cold perfusion.
R.G. Elmslie, R.C. Pirola, N. Coroneos and J.M. Ham.
Surg. Gynec. & Obstet. 1970, 131:694-696.

20.    The effect of oral trypsin inhibitor on pancreatic damage in the rat.
R.C. Pirola, I.P. Beswick and I.A.D. Bouchier.
Brit. J. Exp. Path. 1971, 52:244-251.

21.    The  cause of pancreatic enlargement in rats fed raw soybean.
I.P. Besick, R.C. Pirola and I.A.D. Bouchier.
Brit. J. Exp. Path. 1971, 52:252-255.

22.    The energy cost of the metabolism of drugs, including ethanol.
R.C. Pirola and C.S. Lieber.
Pharmacology. 1972. 7:185-196.

23.    Pathogenesis of post prandial hyperlipemia in rats fed ethanol-containing diets.
E. Baraona, R.C. Pirola and C.S. Lieber.
J. Clin. Invest. 1973, 52:296-303.

24.    Small intestinal damage and changes in cell population produced by ethanol ingestion in the rat.
E. Baraona, R.C. Pirola and C.S. Lieber.
Gastroenterology. 1974, 66:226-234.

25.    Acute and chronic effects of ethanol on intestinal lipid metabolism.
E. Baraona, R.C, Pirola and C.S. Lieber.
Biochim. Biophys. Acta. 1975, 388:19-28.

26.    Energy wastage in rats given drugs that induce microsomal enzymes.
R.C. Pirola and C.S. Lieber.
J. Nutrition.    1975, 105:1544-1548.

27.    Hypothesis: Energy wastage in alcoholism and drug abuse:
Possible role of hepatic microsomal enzymes.
R.C. Pirola and C.S. Lieber.
Am. J. Clin. Nutr. 1976. 29:90-93.

28.    Diagnostic value of serum lipoprotein X in jaundice.
R.C. Pirola, G. Thompson and C. Cordess.
Med. J. Aust. 1976. 1:886-887.

29.    Influence of ethanol on pancreatic lipid metabolism.
J.B. Somer, G. Thompson and R.C. Pirola.
Alcoholism. 1980, 4:341-345.

30.    Gallstones – Treat medically or operate?
R.C. Pirola.
Australian Pescriber. 1980, 4:86-87.

31.    Hemangioendothelial sarcoma of the liver associated with long-term estrogen therapy in man.
J.M. Ham, R.C. Pirola and R.L. Crouch.
Dig. Dis. Sci. 1980, 25:879-883.

32.    Further studies of the ethanol-induced changes in pancreatic lipid metabolism.
J.B. Somer, P. Colley and R.C. Pirola.
Exp. Mol. Path. 1980, 33:231-239.

33.    Increased de novo phospholipid biosynthesis in the stimulated rat exocrine pancreas.
H. Patapanian, R.C. Pirola and J.B. Somer.
Biochem. Biophys. Res. Commun. 1981, 99:319-323.

34.    Ethanol-induced changes in cardiac lipid metabolism. J.B. Somer, P.W. Colley, R.C. Pirola and J.S. Wilson.
Alcoholism. 1981, 5:536-539.

35.    Clinical relevance of alcohol-drug interactions.
C.S. Lieber and R.C. Pirola.
Advances in alcohol and substance abuse, 1982, 1:41-65.

36.     Alcohol causes a fatty pancreas: A rat model of ethanol induced pancreatic steatosis.
J.S. Wilson, P.W. Colley, L. Sosula, R.C. Pirola, B.A. Chapman and J.B Somer.
Alcoholism. 1982, 6:117-121.

37.    Pathogenesis of alcoholic pancreatitis (continuing education review).
J.S. Wilson and R.C. Pirola.
Aust. N.Z. J. Med. 1983, 13:307-312.
38.    Increased phospholipid synthesis in the stimulated rat and human pancreas.
B.A. Chapman, J.S. Wilson, P.W.Colley, R.C. Pirola and J.B. Somer.
Biochem. Biophys. Res. Commun. 1983, 115:771-776.

39.    Evidence for an inherited predisposition to alcoholic pancreatitis. A controlled HLA typing study.
J.S. Wilson, D. Gossat, A. Tait, S. Rouse, Xu Jeng Juan and R.C. Pirola.
Dig. Dis. Sci. 1984, 41:727-730.

40.    Chronic ethanol feeding causes accumulation of serum cholesterol in rat pancreas.
J.S. Wilson, J.B. Somer and R.C. Pirola.
Exp. Mol. Path. 1984, 41:289-297.

41.    Diet and drinking habits in relation to the development of alcoholic pancreatitis.
J.S. Wilson, L. Bernstein, C. McDonald, A. Tait,
D. McNeil and R.C. Pirola.
Gut, 1985, 26:882-887.

42.    Decrease in lipogenesis and glucose oxidation of rat adipose tissue after chronic ethanol feeding.
J. S. Wilson, M.A. Korsten, P.W. Colley and R.C. Pirola.
Biochem. Pharmacol. 1986, 35:2025-2028.

43.    Enprostil and ranitidine.  Comparative safety and efficacy in patients with duodenal ulcer.
M. Mackinnon, J. Duggan, M. Alp, R.C. Pirola,
W.I. Austad, M. Thomas, D. Byrnes, M. Ward and A. Cowen.
Aust. N.Z. J. Med. 1987, 17:316-320.

44.    The incorporation of (myo-2-3H) inositol into phosphatidyl inositol of stimulated rat pancreas.
B.A. Chapman, H. Patapanian, N.R. Pattinson, J.S. Wilson, R.C. Pirola and J.B. Somer.  Biochem. Internat. 1987, 14:697-705.

45.    Chronic ethanol administration depresses fatty acid synthesis in rat adipose tissue.
J.S. Wilson, M.A. Korsten, L.P. Donnelly, P.W. Colley,
J.B. Somer and R.C. Pirola.
Biochem. J. 1988, 251:547-551.

46.  Inhibition of rat adipose tissue fatty acid synthesis by chronic ethanol feeding.
J.S. Wilson, P.W. Colley, M.A. Korsten, L.P. Donnelly and R.C. Pirola.
Biochem. J. 1988, 251:547-551.
47.    Alcohol-induced pancreatic injury – Unexplained clinical features and ductular theories of pathogenesis.
J.S. Wilson, M.A. Korsten, and R.C. Pirola.
Int. J. Pancreat. 1989, 4:109-125.

48.    Alcohol-induced pancreatic injury – Evolution of pathogenetic theories.
J.S. Wilson, M.A. Korsten and R.C. Pirola.
Int. J. Pancreat. 1989, 4:233-250.

49.    Both ethanol consumption and protein deficiency increase the fragility of pancreatic lysosomes.
Jeremy S. Wilson, Mark A. Korsten, Minoti V. Apte, Mervyn C. Thomas, Paul S. Haber and Romano C. Pirola.
J. Lab. Clin. Med. 1990, 115:749-755.

50.    The drinker’s pancreas.  Enhanced synthesis of zymogens, secretory block and lysosomal fragility in the pathogenesis of alcoholic pancreatitis.
Jeremy S. Wilson, Mark A. Korsten, Mervyn C. Thomas and Romano C. Pirola.
Int. J. Pancreat. 1990, 5:343-350.

51.    Alpha-1-antitrypsin phenotypes and alcoholic pancreatitis.

P.S. Haber, J.S. Wilson, B.M. Mcgarity, W. Hall, M.C. Thomas and R.C. Pirola. Gut 32:945-948, 1991.

52.    Effects  of ethanol, acetaldehyde and cholesteryl esters. Ethanol and protein deficiency on pancreatic lysosomes.
J.S. Wilson, M.V. Apte, M.C. Thomas, P.S. Haber and R.C. Pirola.
Gut 33:1099-1104, 1992.

53.    Fatty acid ethyl esters increase rat pancreatic lysosomal fragility.
Paul S. Haber, Jeremy S. Wilson, Minoti V. Apte and Romano C. Pirola.
J. Lab. Clin. Med. 1993, 121:759-764.

54.    Smoking and alcoholic pancreatitis.
P.S. Haber, J.S. Wilson and R.C. Pirola.
Pancreas 8:568-572, 1993.

55.    Lipid intolerance does not account for susceptibility to alcoholic and gallstone pancreatitis.
P.S. Haber, J.S. Wilson, M.V. Apte and R.C. Pirola.
Gastroenterology, 106:742-748, 1994.

56.    The effect of ethanol on rat pancreatic zymogen granules.
P.S. Haber, J.S. Wilson, M.V. Apte and R.C. Pirola.
Gut, in press.

57.    Ethanol alters the content and gene expression of rat pancreatic digestive and lysosomal enzymes.
M. V. Apte, J.S. Wilson, M.A. Korsten, G.W. McCaughan, P.S. Haber and R.C. Pirola.
Gastroenterology.
58.    Chronic ethanol consumption increases the fragility of rat pancreatic zymogen granules.
P.S. Haber, J.S. Wilson, M.V. Apte, M.A. Korsten and R.C. Pirola.
Gut 35:1474-1478, 1994.

59.    Individual susceptibility to alcoholic pancreatitis – still an enigma.
P.S. Haber, J.S. Wilson, M.V. Apte, M.A. Korsten and R.C. Pirola.
J. Lab. Clin. Med, 1995. 125:305-312.

60.    Ethanol-induced alterations in messenger RNA levels correlate with glandular content of pancreatic enzymes.
M.V. Apte, J.S. Wilson, G.W. McCaughan, M.A. Korsten, P.S. Haber, I.D. Norton and R.C. Pirola.
J. Lab. Clin. Med. 1995, 125:634-640.

61.    Effects of ethanol and protein deficiency on pancreatic digestive and lysosomal enzymes.
M.V. Apte, J.S. Wilson, M.A. Korsten, G.W. McCaughan, P.S. Haber and R.C. Pirola.
Gut 36:287-293. 1995.

62.    Both ethanol and protein deficiency increase mRNA levels for pancreatic lithostathine.
M.V. Apte, J.S. Wilson, G.W. McCaughan, M.A. Korsten and R.C. Pirola.
Life Sciences 58:485-492. 1996.

63.  Management of acute pancreatitis.
P.S. Haber and R.C.Pirola
J.Gast. & Hep. 1997.

64. The Drinker’s Pancreas: Molecular mechanisms begin to emerge (Editorial).
J.Wilson and R.C.Pirola
Gastroenterology 1997, 113:355-358.

65. Chronic ethanol administration decreases rat pancreatic GP2 content.
M.V.Apte, I.D.Norton, P.S.Haber, G.W.McCaughan, M.A.Korsten, R.C.Pirola and J.S.Wilson
Biochim. Biophys. Acta 1997, 1336:89-98.

66.    The effect of ethanol on pancreatic enzymes – a dietary artefact?
M.V.Apte, I.D.Norton, P.S.Haber, T.L.Applegate, M.A.Korsten, R.C.Pirola and J.S.Wilson
Biochim. Biophys. Acta  1998, 1379: 314-324.

67.    Cytochrome P4502E1 is present in rat pancreas and is induced by chronic ethanol administration.
I.D.Norton, M.V.Apte, P.S.Haber, T.N.Applegate, R.C.Pirola and J.S.Wilson
Gut 1998, 42:426-430.

68.        Cystic fibrosis genotypes and alcoholic pancreatitis.
I.D.Norton, M.V.Apte, P.S.Haber, R.Trent, R.C.Pirola and J.S.Wilson
J. Gastroenterol. Hepatol. 1998, 13:496-500.

69.          Periacinar stellate shaped cells in rat pancreas: identification, isolation and culture of stellate cells from rat pancreas.
M.V.Apte, P.S.Haber, T.L.Applegate, I.D.Norton, G.W.McCaughan, M.A.Korsten, R.C.Pirola and J.S.Wilson
Gut 1998, 43:128-133.

70.          Chronic ethanol administration causes oxidative stress in    the rat pancreas.
I.D.Norton, M.V.Apte, O.Lux, P.S.Haber, R.C.Pirola and J.S.Wilson
J. Lab. Clin. Med. 1998, 131:442-446.

71.         Metabolism of ethanol by rat pancreatic acinar cells.
P.S.Haber, M.V.Apte, T.L.Applegate, I.D.Norton, M.A.Korsten, R.C.Pirola and J.S.Wilson
J Lab Clin Med 1998, 132:294-302.

72.         Alcoholic pancreatitis and polymorphisms of the variable length polythymidine tract in the cystic
fibrosis (CFTR) gene.
P.S.Haber, M.D.Norris, M.V.Apte, S.C.Rodgers, I.D.Norton, R.C.Pirola, I.C.Roberts-Thomson and J.S.Wilson.
Alcoholism Clinical and Experimental Research 1999, 23:509-512.

73.     Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis.
M.V.Apte, P.S.Haber, S.J.Darby, S.C.Rodgers, R.C.Pirola, M.A.Korsten, G.W.McCaughan and J.S.Wilson.
Gut 1999, 44:534-541.
(See Comment: in Gut, 44:451-452, 1999)

74. Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis.
P.S.Haber, G.W.Keogh, M.V.Apte, C.S.Moran, N.L.Stewart, D.H.G.Crawford, R.C.Pirola, G.W.McCaughan, G.A.Ramm and J.S.Wilson.
Am J Path, 1999, 155:1087-1095.

75.        MJA Practice Essentials – 12.Pancreatic Disease
G.W.Keogh and R.C.Pirola
Med J Aust 1999, 170:228-234.

76.         Acute Hepatitis C
G.Marinos, R.Pirola and S.Locarnini
Aust Family Physician 1999, 28:SI24-26.

77.        Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells.
M.V.Apte, P.A.Phillips, R.G.Fahmy, S.J.Darby, S.C.Rodgers, G.W.McCaughan, M.A.Korsten, R.C.Pirola, D.Naidoo and J.S.Wilson
Gastroenterology 2000, 118:780-794

78.         Alcohol and the pancreas.
P. Haber, M. Nakamura, K. Tsuchimoto, H. Ishii, G.W. Keogh, M.V. Apte, C.S. Moran, N.L. Stewart, D.H. Crawford, R.C. Pirola, G.W. McCaughan, G.A. Ramm, J.S. Wilson, H. Nishino, M. Kohno, R. Aizawa, N. Tajima, K. Maruyama, H. Takahashi, S. Matsushita, K. Okuyama, A. Yokoyama, Y. Nakamura, K. Shirakura, H. Ishii, K.M. Conigrave, B.F. Hu, C.A. Camargo Jr, M.J. Stampfer, W.C. Willett and E.B. Rimm.
Alcoholism: Clinical & Experimental Research. 25 (5 Suppl ISBRA): 244S-250S, 2001

79.         Polymorphism in alcohol-metabolizing enzymes, glutathione S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and pancreatitis.
A.Frenzer, W.J.Butler, I.D.Norton, J.S.Wilson, M.V. Apte, R.C.Pirola, P. Ryan and I.C.Roberts-Thomson
Journal of Gastroenterology and Hepatology, 17: 177-182, 2002

80.         Pancreatic  stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis.
P.J. Mews, P.A. Phillips, R.A. Fahmy, R.C. Pirola, M.A. Korsten, J.S. Wilson, M.V. Apte.
Gut 50:535-541, 2002

81.         Pancreatic stellate cells secrete matrix metalloproteinases: implications for extracellular matrix turnover.
Phillips PA, McCarroll JA, Park S, Wu MJ, Pirola R, Korsten M, Wilson JS, Apte MV.
Gut, 52:275-282, 2003.

82.         Cell migration : A novel aspect of pancreatic stellate cell biology.
Phillips PA, Wu MJ, Doherty E, Kumar RK, McCarroll JA, Park S, Pirola RC, Wilson JS, Apte MV.
Gut, 2003; 52:677-682.

83.         Pancreatic stellate cell activation by ethanol and acetaldehyde: is it mediated by the mitogen-activated protein kinase (MAPK) signaling pathway?
McCarroll, J, Phillips P, Park S, Doherty E, Pirola R, Wilson J, Apte M.
Pancreas, 2003, 27: 150-160.

84.         Pancreatic stellate cell migration: role of the phosphatidylinositol 3-kinase (PI3-kinase) pathway
McCarroll JA, Philips PA, Kumar RK, Park S, Pirola RC, Wilson JS, Apte MV.
Biochem Pharmacol, 2004, 67: 1215-1225

85.     Non-oxidative metabolism of ethanol by rat pancreatic acini. Pancreatology
Haber PS, Apte MV, Moran C, Applegate TL, Pirola RC, Korsten MA, McCaughan GW, Wilson JS.,
Pancreatology 2004; 4:82-89

86.     Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells.
MV Apte, S Park, PA Phillips, N Santucci, D Goldstein, RK Kumar, G Ramm, M Buchler, H Friess, JA McCarroll, G Keogh, N Merrett, R Pirola, JS Wildon
Pancreas, 2004 29: 179-187.

87.         Where there’s smoke there’s not necessarily fire. Commentary on ‘Smoking and the progression of alcoholic pancreatitis’ by Maisonneuve et al.
Apte MV, Pirola RC and Wilson JS
Gut, 2005 54:446-447

88.     Vitamin A inhibits pancreatic stellate cell activation: implications for treatment of pancreatic fibrosis.
McCarroll J, Phillips PA, Santucci N, Pirola RC, Wilson JS, Apte MV.
Gut, 2006, 55:79-89

89.     Fatty acid ethyl esters : alcohol’s henchmen in the pancreas? Invited editorial.
Apte MV, Pirola RC, Wilson JS. F,
Gastroenterology, 2006, 130: 992-995.

90.     Molecular Mechanisms of alcoholic pancreatitis
Apte MV, Pirola RC, Wilson JS
Dig Dis., 2005, 23:232-40. Review

91.    Battle-scarred pancreas: Role of alcohol and pancreatic stellate cells in pancreatic fibrosis.
Apte MV, Pirola RC, Wilson JS
J Gastroenterol Hepatol, 2006, Suppl 3: S97-S101

92.     Bacterial endotoxin – a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model. .
Vonlaufen A, Xu ZH, Daniel B, Joshi S, Toi CS, Kumar RK, Pirola R, Wilson J, Apte MV.
Gastroenterology, 2007, 133: 1293-1303

93.     Pancreatic MAP kinase pathways and acetaldehyde
Apte M, McCarroll J, Pirola R, Wilson J
Novartis Found Symp., 2007:285:200-11; discussion 211-6. Review.

94.     Role of alcohol metoabolism in chronic pancreatitis
Vonlaufen A, Wilson JS, Pirola RC, Apte MV
Alcohol Res Health, 2007 30 : 48-54. Review

95.     Pancreatic stellate cells induce pancreatic cancer growth : findings of a novel orthotopic model of pancreatic cancer.
Vonlaufen A, Joshi S, Qu CF, Xu ZH, Parker NR, Toi CS, Pirola R, Wilson J, Goldstein D, Apte MV.
Cancer Research, in press (accepted March 2008)

96.     Pancreatic stellate cells and pancreatic cancer cells: an unholy alliance
Vonlaufen A, Phillips PA, Xu ZH, Goldstein D, Pirola RC, Wilson JS, Apte MV.
Cancer Research, invited Review, 2008, 68: 7707-7710

97.     Malnutrition as a cause of chronic pancreatitis: Myth dispelled?
Apte MV, Pirola RC, Wilson JS
J Gastroenterol Hepatol 2008, 23:1312-1314 (Editorial)

98. Alcoholic Pancreatitis. It’s the Alcohol, Stupid
Minoti Apte, Romano Pirola and Jeremy Wilson
Nature Reviews Gastroenterology & Hepatology 2009

99. Obituary. Charles S. Lieber 1931-2009
Paul S. Haber, Romano C. Pirola and Jeremy S. Wilson,
J. Gastroenterol Hepatol 2009, accepted April

100.      Isolation of Quiescent Human Pancreatic Stellate Cells (hPSCs):
A Promising In Vitro Tool for Studies of hPSC Biology
Alain Vonlaufen1,2, Phoebe A. Phillips1,2, Lu Yang1,2, Zhihong Xu1,2, Eva Fiala-Beer1,2,Xuguo Zhang1,2, Romano C. Pirola2, Jeremy S. Wilson1 and Minoti V. Apte1
Pancreatology Accepted Nov 2009

ABSTRACTS in PEER-REVIEWED ARTICLES

1.    R.C. Pirola and A.E. Davis. Effects of ethyl alcohol on pancreatic exocrine function. Aust. Ann. Med. 1967;16:89.

2.    A.E. Davis, R.C. Pirola and S. Bell.  Absorption of phenoxymethyl penicillin in patients with steatorrhoea.   Gut 1967;8:523.

3.    R.C. Pirola and A.E. Davis.  The role of ethyl alcohol in the aetiology of pancreatitis.  Gut 1967;8:526.

4.    R.C. Pirola, J.I. Howell, J.A. Lucy and I.A.D.  Bouchier. Macromolecular assemblies in bile.  Clin. Sci. 1969;37:874.

5.    J.M. Ham, J.R. Turtle, R.C. Pirola, and R.G. Elmslie.Insulin in pig bile. Aust. N.Z. J. Surg. 1969;39:222.

6.    R.C. Pirola, P. Kyd and I.A.D. Bouchier.  Leucine naphthyl amidase activity in rat pancreas.  Clin. Sci. 1970;39:11P.

7.    A.E. Davis, R.C. Pirola and J. Martos.  Alcohol and the pancreas.  Aust. Ann. Med. 1970;2:193.

8.    E. Baraona, R.C. Pirola and C.S. Lieber.  Mechanism of ethanol-induced hyperlipemia.  Proceedings of 4th International Symposium on Drugs affecting Lipid Metabolism, Philadelphia. 1971

9.    E. Baraona, R.C. Pirola and C.S. Lieber.  Mechanism of ethanol-induced hyperlipemia. Adv. Exp. Med. Biol. 1972;26:275.

10.    E. Baraona, R.C. Pirola and C.S. Lieber.  Pathogenesis of alcoholic hyperlipemia.  
J. Clin. Invest. 1972;51:8a.

11.    R.C. Pirola and C.S. Lieber.  Energy cost of ethanol metabolism.  Clin. Res. 1973;21:719.

12.    E. Baraona, R.C. Pirola and C.S. Lieber.  Ethanol damages the small intestine and changes its cell population.  J. Clin. Invest. 1973;52:6a.

13.    J. Somer, G. Thompson and R.C. Pirola.  Pancreatic steatosis an early metabolic effect of alcohol.  Aust. N.Z. J. Med. 1978;8:556.

14.    M.C. Thomas, A.G. Liddlelow, R.C. Pirola and M.E.C. Thorpe.  Hepatic Biopsy: no prognostic value in unresolving hepatitis.  Aust. N.Z. J. Med. 1978;8:560.

15.    L. White, J. Mitchell and R. Pirola.  Emergency endoscopy in young children with gastrointestinal haemorrhage.  Aust. Paed. J. 1979, 15:54.

16.    J. Wilson, P. Colley, R. Pirola and J. Somer.  Alcoholic pancreatic steatosis – an animal model and investigation of mechanisms.  Aust. N.Z. J. Med. 1981;11:228.

17.    J.S. Wilson, J.B. Somer, B.A. Chapman and R.C. Pirola.  Enhanced cholesteryl ester synthesis in the pancreas of rats chronically fed ethanol.  Aust. N.Z. J. Med. 1983;13:106.

18.    J.S. Wilson, B.A. Chapman and R.C. Pirola.  Increased phospholipid synthesis in the stimulated rat and human pancreas.  Aust. N.Z. J. Med. 1983;13:110.

19.    R. Pirola and J.V.L. Colman.  Role of ERCP in abdominal pain.  Aust. N.Z. J. Med. 1983;13:114.

20.    J.S. Wilson, D. Gossat, A. Tait, S. Rouse, Xu Jeng Juan and R.C. Pirola.  Evidence for an inherited predisposition to alcoholic pancreatitis.  Aust. N.Z. J. Med. 1983;13:430.

21.    E. Shi, J.S. Wilson, J.M. Ham and R.C. Pirola.  The effect of chronic ethanol feeding on the hepatic glutathione system in the rat.  Aust. N.Z. J. Med. 1983, 13:442-443.

22.    J.S. Wilson, M.A. Korsten, R.C. Pirola, M.A. Leo and C.S. Lieber.  Ethanol-induced pancreatic steatosis: no evidence of mitochondrial dysfunction.  Gastroenterology 1984;86:1299.

23.    M.C. Thomas, H. Patapanian, B.Yan and R.C. Pirola.  Acetaldehyde inhibition of digestive enzyme release from rat pancreas in vitro.  Aust. N.Z. J. Med. 1985;15:555.

24.    L.P. Donnelly, J.S. Wilson, M.V. Apte and R.C. Pirola.  Chronic ethanol feeding depresses lipogenesis in rat adipose tissue.  Aust. N.Z. J. Med. 1987;18:25.

25.    J.S. Wilson, M.A. Korsten, C.S. Leiber and R.C. Pirola.  Pancreatic effects of ethanol and protein deficiency.  Oral presentation to the Gastroenterological Society of Australia, December 1987.  Aust. N.Z. J. Med. 1988;18:185.

26.    J.S. Wilson, L.P. Donnelly, M.V. Apte and R.C. Pirola.  Effects of ethanol and protein deficiency on pancreatic lysosomes.  Oral presentation to the Gastroenterological Society of Australia, May 1988.  Aust. N.Z. J. Med. 1989;18:68.

27.    J.S. Wilson, M.A. Korsten, L.P. Donnelly and R.C. Pirola.  Both ethanol consumption and protein deficiency increase the fragility of pancreatic lysosomes.  Gastroenterology 1988; 94:A499.

28.    P.S. Haber, J.S. Wilson, W. Hall, B. McGarity, M.C. Thomas and R.C. Pirola.  Alpha-1-antritrypsin phenotypes and alcoholic pancreatitis.  Aust. N.Z. J. Med. 1990;20:374. Oral presentation to the Gastroenterological Society of Australia, May 1990.

29.    J.S. Wilson, M.V. Apte, M.C. Thomas and R.C. Pirola.  Effect of cholesteryl esters on pancreatic lysosomes. Aust. N.Z. J. Med. 1990;20:376. Oral presentation to the Gastroenterological Society of Australia, May 1990.

30.    P.S. Haber, J.S. Wilson,  W. Hall, B.M. McGarity, M.C. Thomas and R.C. Pirola. Variations in alpha-antitrypsin phenotypes are not associated with alcoholic pancreatitis.  Gastroenterology 1990;98:A218. Poster presentation at the Gastroenterological Society of Australia, May 1990.

31.    J.S. Wilson, M.V. Apte, M.C. Thomas and R.C. Pirola.  Cholesteryl esters may mediate the injurious effects of ethanol and protein deficiency on the pancreas.   Gastroenterology 1990;98:A240.

32.    M.V. Apte, J.S. Wilson, M.C. Thomas and R.C. Pirola.  Effects of ethanol, acetaldehyde and cholesteryl esters on pancreatic lysosomes.  Proceedings of the 1990 World Congress of Gastroenterology.  Poster presentation at the World Congress of Gastroenterology, August, 1990.

33.    P.S. Haber, J.S. Wilson, M.V. Apte and R.C. Pirola.  Fatty acid ethyl esters increase rat pancreatic lysosomal fragility in vitro.  Pancreas 1991; 6:702. Poster presentation at the American Pancreatic Association, October, 1991.

34.      P.S. Haber, J.S. Wilson and R.C. Pirola.  Does hypertriglyceridaemia predispose to alcoholic pancreatitis?  J Gastroenterol Hepatol. 1992;7:A15. Poster presentation at the Gastroenterological Society of Australia, May, 1992.

35.    P.S. Haber, J.S. Wilson and R.C. Pirola.  Smoking and alcoholic pancreatitis.  
J Gastroenterol Hepatol. 1992;7:A16. Poster presentation at the Gastroenterological Society of Australia, May, 1992.

36.    P.S. Haber, J.S. Wilson and R.C. Pirola.  Hypertriglyceridemia and alcoholic pancreatitis.  Gastroenterology 1992;102:A268. Poster presentation at the American Gastroenterological Association, May, 1992.

37.    P.S. Haber, J.S. Wilson and R.C. Pirola.  Smoking is not a risk factor for alcoholic pancreatitis.  Gastroenterology 1992;102:A268. Poster presentation at the American Gastroenterological Association, May, 1992.

38.    M.V. Apte, J.S. Wilson, P.S. Haber, M.A. Korsten, G.W. McCaughan and 
R.C. Pirola.  Ethanol and dietary protein deficiency alter gene expression of pancreatic digestive enzymes. Gastroenterology 1993;104:A293. Poster presentation at the American Gastroenterological Association, May 1993.

39.    P.S. Haber, J.S. Wilson, M.V. Apte and R.C. Pirola.  Chronic ethanol administration increases rat pancreatic zymogen granule fragility.  Gastroenterology 1993;104:A307. Poster presentation to the American Gastroenterological Association, May 1993.

41.    M.V. Apte, J.S. Wilson, G.W. McCaughan, P.S. Haber and R.C. Pirola.  Effects of ethanol on gene expression of pancreatic digestive and lysosomal enzymes.  Oral presentation (plenary session) to the Gastroenterological Society of Australia, September, 1993.  J Gastroenterol Hepatol. 1993;8:A25.

M.V. Apte, J.S. Wilson, G.W. McCaughan, M.A. Korsten, P.S. Haber and 
R.C. Pirola.  Ethanol-induced alterations in gene expression correlate with the glandular content of pancreatic enzymes. Gastroenterology, 1994;106:A283. Oral presentation to the American Gastroenterological Association, May, 1994.
M.V. Apte, J.S. Wilson, G.W. McCaughan, M.A. Korsten, P.S. Haber and 
R.C. Pirola.  Ethanol-induced alterations in gene expression correlate with the glandular content of pancreatic enzymes. Poster presentation at the International Society of Biomedical Research into Alcoholism, Gold Coast, June 1994.

44.    M.V. Apte, J.S. Wilson, G.W. McCaughan, M.A. Korsten, I. Norton and R.C. Pirola.  Ethanol and dietary protein deficiency increase gene expression of pancreatic lithostathine. Int J Pancreatology, 16:325, 1994. Oral presentation (plenary session) to the Gastroenterological Society of Australia, September, 1994.

45.    I.D. Norton, M.V. Apte, R. Trent, R.C. Pirola and J.S. Wilson.  Heterozygosity for cystic fibrosis ΔF-508 mutation does not predispose alcoholics to pancreatitis. J Gastroenterol Hepatol. 1994; 9:A89. Poster presentation to the Gastroenterological Society of Australia, September, 1994.

46.    M. Apte, J.S. Wilson, G.W. McCaughan, M. Korsten, I. Norton, R.C. Pirola. Ethanol and dietary protein deficiency increase gene expression of pancreatic lithostathine. International Journal of Pancreatology, 16:325. Oral presentation at the International Association of Pancreatology Meeting, November, 1994.

47.    I.D. Norton, M.V. Apte, M. Veronese, G.W. McCaughan, R.C. Pirola and J.S Wilson.  Rat pancreatic cytochrome P-450 2EI (CYP2EI) messenger RNA is not increased by chronic ethanol feeding.  Gastroenterology 1995;108:A380.

48.    I.D. Norton, M.V. Apte, H. Dixson, R.J. Trent, R.C. Pirola, and J.S. Wilson. Cystic fibrosis heterozygosity and alcoholic pancreatitis. .  Gastroenterology 1995;108:A380. Poster presentation at the American Gastroenterological Association, May, 1995

49.    M.V. Apte, I.D. Norton, P.S. Haber, G.W. McCaughan, M.A. Korsten, R.C. Pirola and J.S. Wilson.   Chronic ethanol administration increases gene expression of GP2 in rat pancreas.  Oral presentation to the American Gastroenterological Association, May, 1995.  Gastroenterology 1995;108:A342.

50.    M.V. Apte, I.D. Norton, P.S. Haber, G.W. McCaughan, M.A. Korsten, R.C. Pirola and J.S. Wilson.  Chronic ethanol administration decreases rat pancreatic GP2 content. J Gastroenterol Hepatol. 1995;10:A27.Oral presentation to the Gastroenterological Society of Australia, October, 1995.

51.    P.S. Haber, M.V. Apte, I.D. Norton,  R.C. Pirola and J.S. Wilson. Does the pancreas metabolise ethanol? J Gastroenterol Hepatol. 1995;10:A34. Oral presentation (plenary session) to the Gastroenterological Society of Australia, October, 1995.

52.    I.D. Norton, M.V. Apte, P.S. Haber, R.C. Pirola,  G.W. McCaughan and J.S. Wilson. P45O2EI is present in rat pancreas and is induced by chronic ethanol administration.  Poster presentation to the American Gastroenterological Association, May, 1996.  Gastroenterology 1996;110:A1280.

53.    P.S. Haber, M.V. Apte, I.D. Norton, M.A. Korsten, R.C. Pirola and J.S. Wilson.  Ethanol oxidation by pancreatic acinar cells is comparable to that of hepatocytes. Gastroenterology 1996;110:A394.Poster presentation to the American Gastroenterological Association, May 1996.

54.    I.D. Norton, M.V. Apte, P.S. Haber, R.C. Pirola, G.W. McCaughan and J.S. Wilson. Cytochrome P-450 2E1 is present in rat pancreas and is induced by chronic ethanol administration. Gastroenterology 1996;110:A394. Oral presentation (plenary session) to the Gastroenterological Society of Australia, Sept 1996.  J Gastroenterol Hepatol. 1996;11:A87.

55.    I.D. Norton, M.V. Apte, P.S. Haber, T.L. Applegate, B.E. Tuch, R.L. Crouch, G.W.McGaughan, R.C. Pirola and J.S. Wilson. Pancreatic apoptosis and oxidant stress in a rat model of chronic iron overload. . J Gastroenterol Hepatol. 1996;11:A113. Poster presentation at to the Gastroenterological Society of Australia, Sept 1996

56.    I. Norton, M. Apte, P. Haber, T. Applegate, B. Tuch, R. Crouch, G. McCaughan, 
R. Pirola, J, Wilson. Pancreatic apoptosis and oxidant stress in a rat model of chronic iron overload. Pancreas 13:A452. Poster presentation to the American Pancreatic Association, November, 1996.

57.     M. Apte, I. Norton, P, Haber, T. Applegate, G. McCaughan, M. Korsten, R. Pirola, J. Wilson. Ethanol-induced increases in pancreatic enzyme content – a dietary artefact? Gastroenterology 112:A426, 1997. Poster presentation to the American Gastroenterological Association, May, 1997.

58.    P.S. Haber, I.D. Norton, M.V. Apte, T.L. Applegate, M.A. Korsten, R.C. Pirola, J.S. Wilson. Identification of stellate cells in the rat pancreas. Gastroenterology 112:A446, 1997. Oral presentation to the American Gastroenterological Association, May, 1997.

59.    M. Apte, P. Haber, T. Applegate, I. Norton, M. Korsten, R. Pirola, J. Wilson. Generation of fatty acid ethyl esters by rat pancreatic acini: comparison of oxidative and non-oxidative ethanol metabolism. Gastroenterology 112:A426, 1997. Poster presentation to the American Gastroenterological Association, May, 1997.

60.     M. Apte, I. Norton, P. Haber, T. Applegate, G. McCaughan, M. Korsten, R. Pirola, J. Wilson. Ethanol-induced increases in pancreatic enzyme content – a dietary artefact?  J Gastroenterol Hepatol 12:A54, 1997. Poster presentation to the Gastroenterological Society of Australia, October, 1997.

61.   I. Norton, M. Apte, P. Haber, O. Lux, R. Pirola, J. Wilson. Chronic ethanol administration causes oxidative stress in the rat pancreas. J Gastroenterol Hepatol 12:A34, 1997. Poster presentation to the Gastroenterological Society of Australia, October, 1997.

62.    M. Apte , P. Haber, T. Applegate, I. Norton, M. Korsten, R. Pirola, J. Wilson. Generation of fatty acid ethyl esters by rat pancreatic acini: comparison of oxidative and non-oxidative ethanol metabolism. J Gastroenterol Hepatol 12:A62, 1997. Oral presentation to the Gastroenterological Society of Australia, October, 1997.

63.   M.V. Apte, P.S. Haber, T.L. Applegate, I.D. Norton, R.C. Pirola, J.S. Wilson. Identification, isolation and culture of stellate cells from rat pancreas. J Gastroenterol Hepatol 12:A69, 1997. Oral (plenary) presentation to the Gastroenterological Society of Australia, October, 1997.

64.     P.S. Haber, I.D. Norton, M.D. Norris, M.V. Apte, R.C. Pirola, I.C. Roberts-Thomson, J.S. Wilson. Is the 5T mutation in intron 8 of the cystic fibrosis gene associated with alcoholic pancreatitis? Gastroenterology 114:A466, 1998. Poster presentation at the annual meeting of the American Gastroenterological Association, May 1998.

65.    P. Haber, G. Keogh, M. Apte , C. Moran, R. Pirola, G. McCaughan, M. Korsten, J. Wilson. Pancreatic stellate cells are activated in human and experimental pancreatic fibrosis. Gastroenterology 114:A466, 1998. Poster presentation at the annual meeting of the American Gastroenterological Association, May 1998.

66.     M.V. Apte, P.S. Haber, C.S. Moran, G.W. McCaughan, M.A. Korsten, R.C. Pirola, J.S. Wilson.  Pancreatic stellate cells produce collagen and other extracellular matrix proteins and exhibit a proliferative response to platelet-derived growth factor (PDGF). Gastroenterology 114:A438, 1998. Oral presentation at the annual meeting of the American Gastroenterological Association, May 1998.

67.    P. Haber, G. Keogh, M. Apte, C. Moran, R. Pirola, G. McCaughan, M. Korsten, J. Wilson. Pancreatic stellate cells are activated in human and experimental pancreatic fibrosis. J Gastroenterol Hepatol 1998;13(suppl):A181. Accepted for oral presentation at the annual meeting of the Gastroenterological Society of Australia, October, 1998.

68.     M.V. Apte, P.S. Haber, C.S. Moran, G.W. McCaughan, M.A. Korsten, R.C. Pirola, J.S. Wilson. Pancreatic stellate cells produce collagen and are activated by proinflammatory cytokines. J Gastroenterol Hepatol 1998;13(suppl):A181. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, October, 1998.

69.   P.S. Haber, I.D. Norton, M.D. Norris, M.V. Apte, S.C. Rodgers, R.C. Pirola, I.C. Roberts-Thomson, J.S. Wilson. Is the 5T mutation in intron 8 of the cystic fibrosis gene associated with alcoholic pancreatitis? J Gastroenterol Hepatol 1998;13(suppl):A165. Poster presentation at the Gastroenterological Society of Australia, October 1998.

70.    P. Haber, G. Keogh, M. Apte, C. Moran, R. Pirola, G. McCaughan, M. Korsten, J. Wilson. Pancreatic stellate cells are activated in human and experimental pancreatic fibrosis. Pancreas 44:437, 1998. Oral presentation at the annual meeting of the American Pancreatic Association, November, 1998.

M.V. Apte, P.S. Haber, S.J. Darby, S.C. Rodgers, G.W. McCaughan, M.A. Korsten, R.C. Pirola , J.S. Wilson. Fibrogenic effect of oxidant stress on pancreatic stellate cells. Pancreas 44:424, 1998. Oral presentation at the annual meeting of the American Pancreatic Association, November, 1998.

72.     W.Sievert, S.Warner, S.Pianko, R.Batey, W.Reed, J.McDonald, R.Pirola,
L.Mollison, S.Bowden and R.de Solom. Efficacy, safety and tolerability of daily high dose interferon alpha2b plus ribavirin for retreatment of HCV infected patients who did not respond to initial interferon monotherapy – an interim report of the Aushep 6 study. J.Gast & Hep. 1999, 14:A143. Oral presentation to the Gastroenterological Society of Australia, Brisbane, October 1999.

M.V.Apte, S.Darby, P.Phillips, R.Fahmy, G.McCaughan,  R.C.Pirola, J.S.Wilson.           Alcohol causes pancreatic fibrosis via activation of pancreatic stellate cells: an in             vitro study. J.Gast & Hep. 1999, 14:A115. Oral presentation at Australian                         Gastroenterology Week, Brisbane, October 1999.

74.    Frenzer A, Butler WJ, Norton ID, Pirola RC, Wilson JS, Roberts-Thomson IC.            Genetic polymorphisms of alcohol dehydrogenase (ADH-3) influence susceptibility to   alcoholic cirrhosis but not chronic pancreatitis. Gastroenterology, 116:A1124, 1999.

75.    Norton I, Butler W, Roberts-Thomson I, Frenzer A, Apte MV, Pirola RC, Wilson JS.    Do polymorphisms in the cytochrome P4502E1 gene predispose heavy drinkers to        pancreatitis or cirrhosis? Gastroenterology, 116:A1153, 1999.

Apte MV, Haber PS, Darby SJ, Rodgers SC, McCaughan GW, Korsten MA,
Pirola, RC, Wilson JS. Activation of pancreatic stellate cells by ethanol and its  metabolite acetaldehyde: implications for alcohol-induced pancreatic fibrosis. Gastroenterology, 116:A1176, 1999. Poster presentation at the annual meeting of the American Gastroenterological Association, May 1999.

77.      Apte M, Darby S, Phillips P, Fahmy R, McCaughan G, Korsten M, Pirola R, Wilson    J. Role of pancreatic stellate cells in the pathogenesis of alcoholic pancreatic fibrosis.   Pancreas, 14:414, 1999. Oral presentation at the annual meeting of the American Pancreatic   Association, November, 1999.

78.      Mews PJ, Phillips PA, Fahmy RG, McCaughan GW, Korsten MA, Pirola RC, Wilson   JS, Apte MV. Pancreatic stellate cells are activated by tumour necrosis factor (TNFa) –   implications for pancreatic fibrogenesis. Gastroenterology 118:A424, 2000. Poster        presentation at the annual meeting of the American Gastroenterological Association,     May 2000.

79.      Mews P, Phillips P, Korsten M, Pirola R, Wilson JS, Apte MV. Collagen synthesis by   pancreatic stellate cells – response to inflammatory cytokines. Digestion 61:258, 2000.   Oral presentation at the European Pancreatic Club, July 2000.

80.      Phillips P, Pirola R, McCaughan G, Korsten M, Wilson J, Apte M. Pancreatic stellate   cells secrete matrix metalloproteinases – implications for extracellular matrix turnover.   Pancreas 21:470, 2000. Submitted to the Gastroenterological Society of Australia, October, 2000 and to the American Pancreatic Association, November, 2000.

81.     Phillips P, Pirola R, McCaughan G, Korsten M, Wilson J, Apte M. Pancreatic stellate cells secrete matrix metalloproteinases – implications for extracellular matrix turnover. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, October, 2000.

82. Apte M, Keating J, Phillips P, Friess H, Buchler M, Kosten M, Pirola R, McCaughan G, Korsten M, Wilson J. Endogenous expression of proinflammatory cytokines and nerve growth factor by pancreatic stellate cells – implications for fibrosis and neural changes in chronic pancreatitis. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, September, 2001.

83. Apte M, Keating J, Phillips P, Friess H, Buchler M, Kosten M, Pirola R, McCaughan G, Korsten M, Wilson J. Endogenous expression of proinflammatory cytokines and nerve growth factor by pancreatic stellate cells – implications for fibrosis and neural changes in chronic pancreatitis. Accepted for oral presentation to the American Pancreatic Association, November, 2001.

84. McCarroll J, Phillips P, Park S, Doherty E, Pirola R, Wilson J, Apte M. Activation of pancreatic stellate cells by ethanol and acetaldehyde is mediated by the mitogen activated protein kinase (MAPK) pathway. J Gast. & Hep. 2002, 17(Suppl): A183. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, Adelaide October 2002.

85. Park S, Phillips P, Kumar RK, Doherty E, McCarroll J, Pirola R, Wilson J and Apte M. Tumour-stromal interactions in the pathogenesis of pancreatic cancer. J Gast. & Hep. 2002, 17(Suppl): A184. Poster presentation at the annual meeting of the Gastroenterological Society of Australia, Adelaide October 2002.

86. Phillips P, Wu M-J, Doherty E, Kumar RK, McCarroll J, Park S, Pirola R, Wilson J, Apte M. Cell migration: a novel aspect of pancreatic stellate cell (PSC) biology. J Gast. & Hep. 2002, 17(Suppl): A184. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, Adelaide October 2002.

87. Park S, Phillips P, Kumar RK, Doherty E, McCarroll J, Pirola R, Wilson J and Apte M. Tumour-stromal interactions in the pathogenesis of pancreatic cancer. Pancreas 2002, 25:444, Oral presentation at the annual meeting of the American Pancreatic Association, November, 2002.

88. McCarroll JA, Phillips PA, Santucci N, Pirola R, Wilson J and Apte M. Vitamin A induces quiescence in culture-activated pancreatic stellate cells – potential as an antifibrotic agent J Gast. & Hep. 2003, 18(Suppl): B122. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, Cairns, Oct 2003.

89. Phillips PA, McCarroll JA, Kumar RK, Park S, Pirola R, Wilson JS and Apte M. Cross-talk between two major platelet derived growth factor (PDGF) – induced signalling pathways in pancreatic stellate cells. J Gast. & Hep. 2003, 18(Suppl): B110. Oral presentation at the annual meeting of the Gastroenterological Society of Australia, Cairns, Oct 2003.

90. McCarroll J, Phillips P, Santucci N, Pirola R, Wilson J, and Apte M. Alcoholic pancreatic fibrosis: role of the phosphatidylinositol-3 kinase (pi3-k) and protein kinase C (PKC) pathways in pancreatic stellate cells. J Gast. & Hep. 2004, 19(Suppl): A245. Oral presentation at a plenary session of the annual meeting of the Gastroenterological Society of Australia, Brisbane, Oct 2004 (First author candidate for Young Investigator Award).

91. Phillips P, McCarroll J, Santucci N, Pirola R, Wilson J and Apte M. Chronic ethanol feeding induces TIMP2 secretion by pancreatic stellate cells – role in alcoholic pancreatic fibrosis. J Gast. & Hep. 2004, 19(Suppl): A249. Oral presentation at annual meeting of the Gastroenterological Society of Australia, Brisbane, Oct 2004.

92.  Santucci N, Phillips P, Park S, Buchler M, Friess H, Goldstein D, McCarroll J, Pirola R, Wilson J and Apte M. Interaction between stromal and epithelial cells: Role in the pathogenesis of pancreatic cancer. J Gast. & Hep. 2004, 19(Suppl): A284. Poster presentation at annual meeting of the Gastroenterological Society of Australia, Brisbane, Oct 2004.

93. Qu CF, Phillips P, Joshi S, Pirola RC, Wilson J, Goldstein D, Apte M. Epithelial-stromal interactions in pancreatic cancer : do pancreatic cancer cells actively recruit host stromal cells for their own benefit? Poster presentation, Peter McCallum Cancer Institute Workshop, Melbourne, November 2005.

94. Qu CF, Phillips P, Joshi S, Pirola RC, Wilson J, Goldstein D, Apte M. Tumour-stromal interactions in pancreatic cancer. Poster presentation, American Association of Cancer Research meeting, Philadelphia, USA April 2005.

95. Joshi S, Vonlaufen A, Xu ZH, Kumar RK, Goldstein D, Pirola RC, Wilson JS, Apte MV. Pancreatic stellate cells stimulate pancreatic cancer growth and metastasis. Evidence from a novel, orthotopic model. Pancreas 33:472, 2006. Oral presentation, American Pancreatic Association meeting, Chicago, November 2006. Awarded the Hirshberg Award for best abstract in pancreatic cancer.

96. A Vonlaufen, S Joshi, CF Qu, PS Phillips, Z Xu, NR Parker, CS Toi, R Pirola, J Wilson, D Goldstein, MV Apte. Pancreatic stellate cells stimulate pancreatic cancer growth and metastasis: findings of a novel orthotopic model of pancreatic cancer. Oral presentation, Australian Gastroenterology Week, Perth, October 2007. (J.Gastroenterol Hepatol 2007, 22 [Suppl. 3]: A420).

97. Phillips PA, Yang L, Vonlaufen A, Xu Z, Pirola R, Wilson JS and Apte MV.
Heat  Shock Proteins are Differentially Regulated during Pancreatic Stellate Cell    Activation. Digestive Diseases Week  2008